Protein engineering with bacterial display

被引：140
|
作者：
Daugherty, Patrick S. [1 ]
机构：
[1] Univ Calif Santa Barbara, Dept Chem Engn Biomol Sci & Engn, Santa Barbara, CA 93106 USA
[2] Univ Calif Santa Barbara, Inst Collaborat Biotechnol, Santa Barbara, CA 93106 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2007年 / 17卷 / 04期
关键词：
D O I：
10.1016/j.sbi.2007.07.004
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent improvements in bacterial surface display systems coupled with efficient selection and screening strategies are propelling bacterial display systems to the forefront of peptide and protein engineering. The ability to analyze and screen very large protein libraries using cell-sorting instrumentation coupled with the ease of manipulating bacteria provides new capabilities for the protein engineering toolbox.
引用
收藏
页码：474 / 480
页数：7
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