Coating of human mesenchymal cells in 3D culture with bioinorganic nanoparticles promotes osteoblastic differentiation and gene transfection

被引：58
|
作者：
Gonzalez-McQuire, Rosanna
Green, David W.
Partridge, Kris A.
Oreffo, Richard O. C.
Mann, Stephen
Davis, Sean A. [1 ]
机构：
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
[2] Univ Southampton, Dev Origins Hlth & Dis, Bone & Joint Res Grp, Southampton SO16 6YD, Hants, England
来源：
ADVANCED MATERIALS | 2007年 / 19卷 / 17期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1002/adma.200602770
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mesenchymal cells are modified in suspension with bio-functionalized calcium phosphate nanoparticles using a scaffold-free cell decoration method. Coated cells remain viable and retain functionality, with cell activity stimulated by the structure and composition of the coating.
引用
收藏
页码：2236 / +
页数：6
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