Antimicrobial susceptibilities of clinical Desulfovibrio isolates

The antimicrobial susceptibilities of 16 clinical isolates of Desulfovibrio spp. were determined. All or most isolates were susceptible to imipenem (MIC90 [MIC at which 90% of the isolates tested were inhibited], 0.5 mug/ml), metronidazole (MIC90, 0.25 mug/ml), clindamycin (MIC90, 4 mug/ml), and chloramphenicol (MIC90, 16 mug/ml) but were resistant or intermediate to penicillin G (MIC90, 64 mug/ml), piperacillin (MIC90, 256 mug/ml), piperacillin-tazobactam (MIC90, 256 mug/ml), cefoxitin (MIC90, > 256 mug/ml), and cefotetan (MIC90, 64 mug/ml). Among isolates with decreased susceptibility to beta -lactams (n = 15), only six were beta -lactamase positive and susceptible to amoxicillin-clavulanate and ticarcillin-clavulanate.