Achieving Elimination as a Public Health Problem for Schistosoma mansoni and S. haematobium: When Is Community-Wide Treatment Required?

被引：23

作者：

Toor, Jaspreet ^{[1
]}

Rollinson, David ^{[2
,3
]}

Turner, Hugo C. ^{[4
,5
]}

Gouvras, Anouk ^{[3
]}

King, Charles H. ^{[6
]}

Medley, Graham F. ^{[7
]}

Hollingsworth, T. Deirdre ^{[1
]}

Anderson, Roy M. ^{[8
,9
,10
]}

机构：

[1] Univ Oxford, Li Ka Shing Ctr Hlth Informat & Discovery, Big Data Inst, Oxford, England

[2] Nat Hist Museum, Dept Life Sci, London, England

[3] Nat Hist Museum, Dept Life Sci, Global Schistosomiasis Alliance, London, England

[4] Univ Oxford, Wellcome Trust Major Overseas Programme, Clin Res Unit, Ho Chi Minh City, Vietnam

[5] Univ Oxford, Ctr Trop Med & Global Hlth, Nuffield Dept Med, Oxford, England

[6] Case Western Reserve Univ, Ctr Global Hlth & Dis, Cleveland, OH 44106 USA

[7] London Sch Hyg & Trop Med, Ctr Math Modelling Infect Dis, London, England

[8] Imperial Coll London, London Ctr Neglected Trop Dis Res, Dept Infect Dis Epidemiol, London, England

[9] Imperial Coll London, Med Res Council Ctr Global Infect Dis Anal, Sch Publ Hlth, Dept Infect Dis Epidemiol, London, England

[10] Nat Hist Museum, DeWorm3 Project, London, England

来源：

JOURNAL OF INFECTIOUS DISEASES | 2019年 / 221卷

基金：

英国惠康基金;

关键词：

schistosomiasis; mass drug administration; school-based treatment; community-wide treatment; elimination as a public health problem; TRANSMISSION;

D O I：

10.1093/infdis/jiz609

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The World Health Organization (WHO) has set elimination as a public health problem (EPHP) as a goal for schistosomiasis. As the WHO treatment guidelines for schistosomiasis are currently under revision, we investigate whether school-based or community-wide treatment strategies are required for achieving the EPHP goal. In low- to moderate-transmission settings with good school enrolment, we find that school-based treatment is sufficient for achieving EPHP. However, community-wide treatment is projected to be necessary in certain high-transmission settings as well as settings with low school enrolment. Hence, the optimal treatment strategy depends on setting-specific factors such as the species present, prevalence prior to treatment, and the age profile of infection.

引用

页码：S525 / S530

页数：6

共 6 条

[1] How Does Treatment Coverage and Proportion Never Treated Influence the Success of Schistosoma mansoni Elimination as a Public Health Problem by 2030?
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[J]. CLINICAL INFECTIOUS DISEASES, 2024, 78 : S126 - S130
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[4] THE PLANNING OF A COMMUNITY-HEALTH MODEL PROJECT IN AN AREA IN EGYPT (EL-QALYUB) WITH CONCOMITANT OCCURRENCE OF S-MANSONI AND SCHISTOSOMA-HAEMATOBIUM
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