We prove that a differential field K is algebraically closed and Picard-Vessiot closed if and only if the differential Galois cohomology group, H-theta(1)(K, G), is trivial for any linear differential algebraic group G over K. We give applications to the parameterized Picard-Vessiot theory and pose several problems. (C) 2017 Elsevier Masson SAS. All rights reserved.