An asymmetrical CLL1/CD3 bispecific antibody, ABL602, exhibits CLL1 binding-dependent CD3 binding/activation and antitumor activity in acute myeloid leukemia (AML) mouse model and leukemia blasts from AML patients

被引:1
|
作者
Lee, E. [1 ]
Lim, Y. [1 ]
Lee, S. [1 ]
Park, S. [1 ]
Park, H. [1 ]
Koh, Y. [2 ]
Shin, D. [2 ]
Won, J. [1 ]
机构
[1] ABL Bio Inc, Early Res Dev, Seongnam, South Korea
[2] SNUH Seoul Natl Univ Hosp, Hematol Oncol Dept, Seoul, South Korea
关键词
D O I
10.1016/j.annonc.2022.07.748
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
622MO
引用
收藏
页码:S828 / S829
页数:2
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