THE EFFICACY AND SAFETY OF TRANEXAMIC ACID TREATMENT IN ORTHOPAEDIC TRAUMA SURGERY

被引：2
|
作者：
Perskin, Cody R. [1 ]
Littlefield, Connor P. [1 ]
Wang, Charles [1 ]
Umeh, Uchenna [1 ]
Egol, Kenneth A. [1 ]
机构：
[1] NYU, Langone Orthoped Hosp, New York, NY 10010 USA
来源：
JBJS REVIEWS | 2021年 / 9卷 / 07期
关键词：
TOTAL JOINT ARTHROPLASTY; BLOOD-LOSS; CALCANEAL FRACTURES; CLINICAL-TRIAL; DOUBLE-BLIND; HIP; TRANSFUSION; COST; COAGULATION; HEMORRHAGE;
D O I：
10.2106/JBJS.RVW.20.00292
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
>> Tranexamic acid (TXA) is a drug used to control hemorrhage by preventing the breakdown of fibrin. >> TXA is a cost-effective treatment for trauma patients across a variety of economic settings. >> Concerns of TXA causing thromboembolic events (TEEs) in orthopaedic trauma patients are not supported by evidence. >> TXA has been shown to reduce blood loss in hip fracture surgery.
引用
收藏
页数：8
相关论文
共 50 条
  • [1] Efficacy and safety of tranexamic acid in orthopaedic trauma surgery: a meta-analysis
    Hu, M.
    Liu, Z-B
    Bi, G.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (24) : 11025 - 11031
  • [2] Tranexamic Acid in Orthopaedic Trauma Surgery: A Meta-Analysis
    Gausden, Elizabeth B.
    Qudsi, Rameez
    Boone, Myles D.
    O'Gara, Brian
    Ruzbarsky, Joseph J.
    Lorich, Dean G.
    JOURNAL OF ORTHOPAEDIC TRAUMA, 2017, 31 (10) : 513 - 519
  • [3] Safety and Efficacy of Tranexamic Acid in General Surgery
    Park, Lily J.
    Marcucci, Maura
    Ofori, Sandra N.
    Borges, Flavia K.
    Nenshi, Rahima
    Kanstrup, Charlotte Tiffanie Bendtz
    Rosen, Michael
    Landoni, Giovanni
    Lomivorotov, Vladimir
    Painter, Thomas W.
    Xavier, Denis
    Martinez-Zapata, Maria Jose
    Szczeklik, Wojciech
    Meyhoff, Christian S.
    Chan, Matthew T. V.
    Simunovic, Marko
    Bogach, Jessica
    Serrano, Pablo E.
    Balasubramanian, Kumar
    Cadeddu, Margherita
    Yang, Ilun
    Kim, Won Ho
    Devereaux, P. J.
    JAMA SURGERY, 2025, 160 (03) : 267 - 274
  • [4] Efficacy and Safety of Tranexamic Acid in Orthopaedic Fracture Surgery: A Meta-Analysis and Systematic Literature Review
    Amer, Kamil M.
    Rehman, Saqib
    Amer, Kamal
    Haydel, Christopher
    JOURNAL OF ORTHOPAEDIC TRAUMA, 2017, 31 (10) : 520 - 525
  • [5] Efficacy and Safety of Tranexamic Acid in Bimaxillary Orthognathic Surgery
    Sun, Liang
    Guo, Rui
    Feng, Yi
    PLASTIC SURGERY, 2020, 28 (02) : 94 - 104
  • [6] The Efficacy and Safety of Topical Tranexamic Acid for Spinal Surgery
    Guo, Tai
    Xuan, Wenxia
    Feng, Haoyu
    Wang, Junjie
    Ma, Xun
    CURRENT PHARMACEUTICAL DESIGN, 2021, 27 (44) : 4496 - 4503
  • [7] Efficacy and Safety of Tranexamic Acid Versus ε-Aminocaproic Acid in Cardiovascular Surgery
    Falana, Olabisi
    Patel, Gourang
    ANNALS OF PHARMACOTHERAPY, 2014, 48 (12) : 1563 - 1569
  • [8] Safety and efficacy of tranexamic acid in the application of spinal tuberculosis surgery
    Geng, Tongyu
    Chen, Yingjun
    Zhang, Lei
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2017, 10 (02): : 3561 - 3567
  • [9] Tranexamic Acid: When is It Indicated in Orthopaedic Surgery?
    Viberg, Bjarke
    ZEITSCHRIFT FUR ORTHOPADIE UND UNFALLCHIRURGIE, 2023, 161 (04): : 379 - 384
  • [10] Safety and efficacy of use of demineralised bone matrix in orthopaedic and trauma surgery
    Dinopoulos, Haralampos T. H.
    Giannoudis, Peter V.
    EXPERT OPINION ON DRUG SAFETY, 2006, 5 (06) : 847 - 866
12345