GAB1 SCAFFOLDING ADAPTOR PROTEIN PROTECTS FROM LIVER FIBROSIS DURING CHRONIC LIVER INJURY IN MICE

被引：0
|
作者：
Kizu, Takashi [1 ]
Yoshida, Yuichi [1 ]
Takemura, Takayo [1 ]
Furuta, Kunimaro [1 ]
Kamada, Yoshihiro [1 ]
Chatani, Norihiro [1 ]
Hamano, Mina [1 ]
Tsubakio, Mayumi [1 ]
Ezaki, Hisao [1 ]
Kiso, Shinichi [1 ]
Takehara, Tetsuo [1 ]
机构：
[1] Osaka Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Osaka, Japan
来源：
HEPATOLOGY | 2011年 / 54卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：741A / 741A
页数：1
相关论文
共 50 条
  • [1] Loss of Gab1 scaffolding adaptor protein in the hepatocytes exacerbates cholestasis-induced liver fibrosis in mice
    Kizu, Takashi
    Yoshida, Yuichi
    Furuta, Kunimaro
    Ogura, Satoshi
    Egawa, Mayumi
    Chatani, Norihiro
    Hamano, Mina
    Ezaki, Hisao
    Komodo, Yoshihiro
    Kiso, Shinichi
    Takehara, Tetsuo
    HEPATOLOGY, 2013, 58 : 572A - 572A
  • [2] Loss of Gab1 adaptor protein in hepatocytes aggravates experimental liver fibrosis in mice
    Kizu, Takashi
    Yoshida, Yuichi
    Furuta, Kunimaro
    Ogura, Satoshi
    Egawa, Mayumi
    Chatani, Norihiro
    Hamano, Mina
    Takemura, Takayo
    Ezaki, Hisao
    Kamada, Yoshihiro
    Nishida, Keigo
    Nakaoka, Yoshikazu
    Kiso, Shinichi
    Takehara, Tetsuo
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2015, 308 (07): : G613 - G624
  • [3] GAB1 SCAFFOLDING ADAPTOR PROTEIN IS REQUIRED FOR STEM/PROGENITOR CELL MEDIATED LIVER REGENERATION IN MICE
    Yoshida, Yuichi
    Kizu, Takashi
    Tsubakio, Mayumi
    Chatani, Norihiro
    Hamano, Mina
    Takemura, Takayo
    Ezaki, Hisao
    Kamada, Yoshihiro
    Kiso, Shinichi
    Hayashi, Norio
    HEPATOLOGY, 2010, 52 (04) : 424A - 424A
  • [4] Gab1 Adaptor Protein Acts As a Gatekeeper to Balance Hepatocyte Death and Proliferation During Acetaminophen-Induced Liver Injury in Mice
    Furuta, Kunimaro
    Yoshida, Yuichi
    Ogura, Satoshi
    Kurahashi, Tomohide
    Kizu, Takashi
    Maeda, Shinichiro
    Egawa, Mayumi
    Chatani, Norihiro
    Nishida, Keigo
    Nakaoka, Yoshikazu
    Kiso, Shinichi
    Kamada, Yoshihiro
    Takehara, Tetsuo
    HEPATOLOGY, 2016, 63 (04) : 1340 - 1355
  • [5] Gab1 adaptor protein is an essential gatekeeper to balance hepatocyte death and proliferation during acetaminophen-induced liver injury in mice
    Yoshida, Yuichi
    Furuta, Kunimaro
    Ogura, Satoshi
    Kura-Hashi, Tomohide
    Egawa, Mayumi
    Kiso, Shinichi
    Kamada, Yoshihiro
    Takehara, Tetsuo
    HEPATOLOGY, 2015, 62 : 326A - 327A
  • [6] Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis
    Mizutani, Naoki
    Hikita, Hayato
    Saito, Yoshinobu
    Myojin, Yuta
    Sato, Katsuhiko
    Urabe, Makiko
    Kurahashi, Tomohide
    Shiode, Yuto
    Sakane, Sadatsugu
    Murai, Kazuhiro
    Nozaki, Yasutoshi
    Kodama, Takahiro
    Sakamori, Ryotaro
    Yoshida, Yuichi
    Tatsumi, Tomohide
    Takehara, Tetsuo
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2021, 320 (06): : G958 - G968
  • [7] Scaffolding Protein IQ Containing GTPase Activating Protein 1 Protects the Liver from Injury
    Sen, Anushna
    Erickson, Hanna
    Anakk, Sayeepriyadarshini
    HEPATOLOGY, 2018, 68 : 875A - 875A
  • [8] Liver Fibrosis Protects Mice From Acute Hepatocellular Injury
    Bourbonnais, Eric
    Raymond, Valerie-Ann
    Ethier, Chantal
    Nguyen, Bich N.
    El-Leil, Marc Saba
    Meloche, Sylvain
    Bilodeau, Marc
    GASTROENTEROLOGY, 2012, 142 (01) : 130 - U284
  • [9] The role of Grb2 associated binder 1 (Gab1) scaffolding adaptor protein on signal transduction in human B cells
    Sármay, G
    Kertész, A
    Takács, B
    Angyal, A
    Medgyesi, D
    Váradi, G
    Tóth, G
    FEBS JOURNAL, 2005, 272 : 323 - 324
  • [10] Grb2-associated binder 1 (Gab1) adaptor/scaffolding protein regulates Erk signal in human B cells
    Angyal, Adrienn
    Medgyesi, David
    Sarmay, Gabriella
    SIGNAL TRANSDUCTION PATHWAYS, PT A: APOPTOTIC AND EXTRACELLULAR SIGNALING, 2006, 1090 : 326 - 331
12345