Dosimetry of 192Ir sources used for endovascular brachytherapy

被引:24
|
作者
Reynaert, N
Van Eijkeren, M
Taeymans, Y
Thierens, H
机构
[1] State Univ Ghent, Fac Med, Dept Biomed Phys, B-9000 Ghent, Belgium
[2] State Univ Ghent Hosp, Dept Radiotherapy, B-9000 Ghent, Belgium
[3] State Univ Ghent Hosp, Dept Cardiol, B-9000 Ghent, Belgium
来源
PHYSICS IN MEDICINE AND BIOLOGY | 2001年 / 46卷 / 02期
关键词
D O I
10.1088/0031-9155/46/2/316
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An in-phantom calibration technique for Ir-192 sources used for endovascular brachytherapy is presented. Three different source lengths were investigated. The calibration was performed in a solid phantom using a Farmer-type ionization chamber at source to detector distances ranging from I cm to 5 cm. The dosimetry protocol for medium-energy x-rays extended with a volume-averaging correction factor was used to convert the chamber reading to dose to water. The air kerma strength of the sources was determined as well. EGS4 Monte Carlo calculations were performed to determine the depth dose distribution at distances ranging from 0.6 mm to 10 cm from the source centre. In this way we were able to convert the absolute dose rate at 1 cm distance to the reference point chosen at 2 mm distance. The Monte Carlo results were confirmed by radiochromic film measurements, performed with a double-exposure technique. The dwell times to deliver a dose of 14 Gy at the reference point were determined and compared with results given by the source supplier (CORDIS). They determined the dwell times from a Sievert integration technique based on the source activity. The results from both methods agreed to within 2% for the 12 sources that were evaluated. A Visual Basic routine that superimposes dose distributions, based on the Monte Carlo calculations and the in-phantom calibration, onto intravascular ultrasound images is presented. This routine can be used as an online treatment planning program.
引用
收藏
页码:499 / 516
页数:18
相关论文
共 50 条
  • [1] A standard dosimetry procedure for 192Ir sources used for endovascular brachytherapy
    Piermattei, A
    Fidanzio, A
    Azario, L
    Russo, A
    Perrone, F
    Capote, R
    Toni, MP
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (23): : 4205 - 4221
  • [2] Dosimetric characteristics of 192Ir sources used in interstitial brachytherapy
    Ghiassi-Nejad, M
    Jafarizadeh, M
    Ahmadian-Pour, MR
    Ghahramani, AR
    [J]. APPLIED RADIATION AND ISOTOPES, 2001, 55 (02) : 189 - 195
  • [3] Patient effective dose from endovascular brachytherapy with 192Ir sources
    Perna, L
    Bianchi, C
    Nicolini, G
    Novario, R
    Tanzi, F
    Conte, L
    [J]. RADIATION PROTECTION DOSIMETRY, 2002, 102 (02) : 121 - 128
  • [4] Dosimetry comparison of 192Ir Sources
    Papagiannis, P
    Angelopoulos, A
    Pantelis, E
    Sakelliou, L
    Baltas, D
    Karaiskos, P
    Sandilos, P
    Vlachos, L
    [J]. MEDICAL PHYSICS, 2002, 29 (10) : 2239 - 2246
  • [5] Radiochromic Film Based Reference Dosimetry System for 192Ir Brachytherapy Sources
    Aldelaijan, S.
    Mohammed, H.
    Tomic, N.
    Liang, L.
    Deblois, F.
    Sarfehnia, A.
    Abdel-Rahman, W.
    Seuntjens, J.
    Devic, S.
    [J]. MEDICAL PHYSICS, 2011, 38 (06) : 3574 - +
  • [6] A standard graphite calorimeter for dosimetry in brachytherapy with high dose rate 192Ir sources
    Guerra, A. S.
    Loreti, S.
    Pimpinella, M.
    Quini, M.
    D'Arienzo, M.
    Astefanoaei, I.
    Caporali, C.
    Bolzan, C.
    Pagliari, M.
    [J]. METROLOGIA, 2012, 49 (05) : S179 - S183
  • [7] Influence of source geometry and materials on the transverse axis dosimetry of 192Ir brachytherapy sources
    Wang, RQ
    Sloboda, RS
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (01): : 37 - 48
  • [8] Determination of Dose at the Reference Point for 192Ir HDR Brachytherapy Sources Using Fricke Dosimetry
    Austerlitz, Carlos
    Benhabib, Sidi
    Zhu, Dengsong
    Mota, Helvecio
    Campos, Diana
    Allison, Ron
    Sibina, Claudio
    [J]. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2008, 31 (06): : 617 - 617
  • [9] Experimental and Monte Carlo endovascular dosimetry of a 192Ir source
    Piermattei, A
    Fidanzio, A
    Azario, L
    Russo, A
    Perrone, F
    Toni, MP
    Capote, R
    [J]. PHYSICA MEDICA, 2003, 19 (02) : 111 - 118
  • [10] Gafchromic film dosimetry of a new HDR 192Ir brachytherapy source
    Ayoobian, Navid
    Asl, Akbar Sarabi
    Poorbaygi, Hosein
    Javanshir, Mohammad Reza
    [J]. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 2016, 17 (02): : 194 - 205