Medical therapies for locally advanced/metastatic kidney cancer

被引：2
|
作者：
Afrit, Mehdi [1 ]
Yahyaoui, Yosra [1 ]
Bouzouita, Aderrazek [2 ]
Hantous, Saoussen [3 ]
Labidi, Soumaya [1 ]
Chebil, Mohamed [2 ]
Ben Miled, Khaoula [3 ,4 ]
Escudier, Bernard [4 ]
Boussen, Hamouda [1 ]
机构：
[1] Hop Abderrahmane Mami, Med Oncol Serv, Tunis 1005, Tunisia
[2] Hop Charles Nicolle, Serv Urol, Tunis 1005, Tunisia
[3] Univ Tunis El Manar, Hop Abderahmane Mami, Serv Radiol, Tunis 1005, Tunisia
[4] Inst Gustave Roussy, Dept Med, F-94805 Villejuif, France
来源：
PRESSE MEDICALE | 2015年 / 44卷 / 02期
关键词：
RENAL-CELL CARCINOMA; INTERFERON-ALPHA; PHASE-3; TRIAL; SURVIVAL; SUNITINIB; NEPHRECTOMY; SORAFENIB; METASTASES; EVEROLIMUS; REMISSION;
D O I：
10.1016/j.lpm.2014.07.020
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Aims > To analyze the medical literature concerning the results of the international randomized muticentric trials concerning therapeutic innovations, mainly targeted therapies in locally advanced and or metastatic renal cell cancer and to evaluate the benefit of these TT Methods > We performed a review of publications that concerned this topic published from 2000 to 2014. Results > They concerned the large randomized trials have showed a benefit of the targeted therapies in the treatment of clear cell carcinomas in terms of progression-free survival. Condusion > Advances in molecular biology have allowed the development of these targeted therapies that have all proved their role in the treatment of metastatic renal cell carcinoma.
引用
收藏
页码：135 / 143
页数：9
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