Identifying the gluc-1 and gluc-2 mutations in Neurospora crassa by genome resequencing

被引：1

作者：

McCluskey, Kevin ^{[1
]}

Baker, Scott E. ^{[2
,3
]}

机构：

[1] Bolt Threads, 5858 Horton, Emeryville, CA 94608 USA

[2] US DOE, Joint BioEnergy Inst, 5885 Hollis St, Emeryville, CA 94608 USA

[3] Pacific Northwest Natl Lab, Funct & Syst Biol Grp, Environm Mol Sci Div, 3335 Innovat Blvd, Richland, WA 99354 USA

来源：

JOURNAL OF GENETICS | 2022年 / 101卷 / 02期

关键词：

resequencing; genomics; beta-glucosidase; phenotype; genotype; Neurospora crassa; BETA-GLUCOSIDASE SYSTEM; MODEL FILAMENTOUS FUNGUS; CELLULASE; PURIFICATION; DEGRADATION; MECHANISMS; INDUCTION; ENZYMES; GENE;

D O I：

10.1007/s12041-022-01394-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genome resequencing is an efficient strategy for associating mutant phenotypes with physical genomic loci (Baker 2009). A pilot study of this approach demonstrated that the Neurospora crassa genetic map was critical in narrowing the possible candidate mutations in a strain to a small number in a limited, defined region of the genome (McCluskey et al. 2011). In this study, we utilize a resequencing strategy to identify the mutations underlying the gluc-1 and gluc-2 genes in N. crassa.

引用

页数：3

共 50 条

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