Studies on the synthesis of apoptolidin A. 2. Synthesis of the disaccharide unit

被引：18
|
作者：
Handa, Masaki [1 ]
Smith, William J., III [2 ]
Roush, William R. [1 ]
机构：
[1] Scripps Florida, Dept Chem, Jupiter, FL 33458 USA
[2] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 03期
关键词：
D O I：
10.1021/jo7022526
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Disaccharide 3 correspoinding to the disaccharide unit of apoptolidin A. has been synthesized via the regio- and stereoselective TBS-OTf-promoted beta-glycosidation reaction of 2,6-dideoxy-2-iodo-beta-glucopyranosyl acetate (5) and p-methoxybenzyl 2,6-dideoxy-2-iodo-3-C-methyl-alpha-mannopyranoside (11).
引用
收藏
页码：1036 / 1039
页数：4
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