Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1)

被引：25

作者：

Bento, Diogo ^{[1
]}

Mapril, Joana ^{[1
]}

Rocha, Carla ^{[1
]}

Marchbank, Kevin J. ^{[2
]}

Kavanagh, David ^{[3
]}

Barge, Dawn ^{[4
]}

Strain, Lisa ^{[5
]}

Goodship, Timothy H. J. ^{[3
]}

Meneses-Oliveira, Carlos ^{[1
]}

机构：

[1] Ctr Hosp Lisboa Ocidental, Hosp Santa Cruz, Intens Care Unit, Lisbon, Portugal

[2] Newcastle Univ, Inst Cellular Med, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[3] Newcastle Univ, Inst Human Genet, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[4] Newcastle Tyne Hosp NHS Fdn Trust, Dept Immunol, Newcastle Upon Tyne, Tyne & Wear, England

[5] Newcastle Tyne Hosp NHS Fdn Trust, No Mol Genet Serv, Newcastle Upon Tyne, Tyne & Wear, England

来源：

RENAL FAILURE | 2010年 / 32卷 / 06期

基金：

英国医学研究理事会;

关键词：

atypical hemolytic uremic syndrome; influenza A H1N1; microangiopathy; renal failure; VIRUS-INFECTION; COMPLEMENT; MUTATIONS; PREDISPOSITION; IMPACT;

D O I：

10.3109/0886022X.2010.486491

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of atypical hemolytic uremic syndrome (aHUS) triggered by influenza A (H1N1) in a 17-year-old boy with a mutation in the gene (CD46) encoding the transmembrane complement regulator membrane cofactor protein. The patient recovered completely following treatment with oseltamivir, plasma exchange, and hemodialysis. We describe the case and discuss this unusual association of diseases.

引用

页码：753 / 756

页数：4

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