A pivotal role of IRS-1/IRS-2 in insulin-stimulated protein synthesis pathway

被引：0
|
作者：
Tobe, K
Yamauchi, T
Tamemoto, H
Akanuma, Y
Yazaki, Y
Kadowaki, T
机构：
来源：
DIABETES | 1996年 / 45卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：914 / 914
页数：1
相关论文
共 50 条
  • [1] IRS-1 but not IRS-2 differentially modulates insulin-stimulated tyrosine phosphorylation of the insulin receptor
    Jarett, L
    Solow, BT
    Harada, S
    Smith, JA
    Goldstein, BJ
    DIABETES, 1999, 48 : A338 - A338
  • [2] mTOR signaling pathway regulates insulin-stimulated ubiquitination of IRS-1
    Kawahara, J
    Haruta, T
    Uno, T
    Takano, A
    Iwala, M
    Kabayashi, M
    DIABETES, 2000, 49 : A242 - A242
  • [3] Grb10 inhibits insulin-stimulated phosphorylation of IRS-1/IRS-2 and delays signaling through the PI 3-kinase pathway
    Wick, KR
    Ramos, FJ
    Dong, LQ
    Liu, F
    DIABETES, 2002, 51 : A325 - A325
  • [4] Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor
    Wick, KR
    Werner, ED
    Langlais, P
    Ramos, FJ
    Dong, LQ
    Shoelson, SE
    Liu, F
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (10) : 8460 - 8467
  • [5] The role of IRS-1 in insulin-stimulated glucose uptake into cultured adipocytes
    Bernal, D
    Brooks, J
    Bruening, J
    Towery, HH
    White, MF
    Yenush, L
    DIABETES, 1997, 46 : 18 - 18
  • [6] Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation
    Miki, H
    Yamauchi, T
    Suzuki, R
    Komeda, K
    Tsuchida, A
    Kubota, N
    Terauchi, Y
    Kamon, J
    Kaburagi, Y
    Matsui, J
    Akanuma, Y
    Nagai, R
    Kimura, S
    Tobe, K
    Kadowaki, T
    MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (07) : 2521 - 2532
  • [7] Differential subcellular signaling by IRS-1 and IRS-2
    Inoue, G
    Cheatham, B
    Kahn, CR
    DIABETES, 1997, 46 : 24 - 24
  • [8] The Phosphotyrosine Interactome of the Insulin Receptor Family and Its Substrates IRS-1 and IRS-2
    Hanke, Stefan
    Mann, Matthias
    MOLECULAR & CELLULAR PROTEOMICS, 2009, 8 (03) : 519 - 534
  • [9] Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells
    Bruning, JC
    Winnay, J
    Cheatham, B
    Kahn, CR
    MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (03) : 1513 - 1521
  • [10] Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
    Kido, Y
    Burks, DJ
    Withers, D
    Bruning, JC
    Kahn, CR
    White, MF
    Accili, D
    JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (02): : 199 - 205
12345