Effect of Monoclonal Antibody Treatment on Clinical Outcomes in Ambulatory Patients With Coronavirus Disease 2019

被引：6
|
作者：
Anderson, Blake [1 ]
Smith, Zirka [2 ]
Edupuganti, Srilatha [2 ]
Yan, Xiaobo [3 ]
Masi, Christopher M. [1 ]
Wu, Henry M. [2 ]
机构：
[1] Emory Univ, Sch Med, Dept Med, Div Gen Internal Med, Atlanta, GA 30308 USA
[2] Emory Univ, Dept Med, Div Infect Dis, Sch Med, Atlanta, GA 30308 USA
[3] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30308 USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2021年 / 8卷 / 07期
关键词：
COVID-19; monoclonal antibodies; SARS-CoV-2; therapeutics;
D O I：
10.1093/ofid/ofab315
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We compared rates of emergency department visits or hospitalizations among ambulatory coronavirus disease 2019 (COVID-19) patients treated with monoclonal antibody (mAb) therapy (n = 305) vs untreated patients (n = 6354). Treatment was associated with decreased encounters within 30 days (adjusted odds ratio, 0.23 [95% confidence interval, .15-.36]). Our findings support treatment of acute COVID-19 with mAbs.
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页数：4
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