A modified procedure for the Dakin-West reaction:: an efficient and convenient method for a one-pot synthesis of β-acetamido ketones using silica sulfuric acid as catalyst

被引：123

作者：

Khodaei, MM ^{[1
]}

Khosropour, AR ^{[1
]}

Fattahpour, P ^{[1
]}

机构：

[1] Razi Univ, Fac Sci, Dept Chem, Kermanshah 67149, Iran

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 12期

关键词：

beta-acetamido ketones; benzaldehydes; acetophenones; one-pot synthesis; silica sulfuric acid; catalyst; Dakin-West reaction;

D O I：

10.1016/j.tetlet.2005.01.149

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot, four-component condensation of an aryl aldehyde, an aryl ketone, acetyl chloride and acetonitrile in the presence of silica sulfuric acid as an active, inexpensive, recoverable and recyclable catalyst is disclosed for the synthesis of beta-acetamido ketones. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：2105 / 2108

页数：4

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