Early low-dose dobutamine echocardiography predicts late functional recovery after thrombolyzed acute myocardial infarction

被引:9
|
作者
Samad, BA
Frick, M
Höjer, J
Urstad, MJ
机构
[1] Soder Hosp, Dept Med, Div Cardiol, Stockholm, Sweden
[2] Huddinge Univ Hosp, Dept Cardiol, Huddinge, Sweden
关键词
D O I
10.1016/S0002-8703(99)70497-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background This study was undertaken to evaluate the ability of predischarge low-dose dobutamine echocardiography to predict late left ventricular functional recovery after thrombolyzed acute myocardial infarction. Methods and Results low-dose dobutaonine echocardiography was performed in 54 patients 4 +/- 2 days after acute myocardial infarction treated with thrombolysis. Follow-up resting echocardiography was carried out in 49 of these patients at a mean of 18 +/- 6 months later. Viability was defined as recovery of myocardial function at Follow-up, expressed as an improvement of wall motion of at least 1 grade or more in at least 2 contiguous infarct zone segments. In 24 of the 49 patients (group I), wall motion at follow-vp improved in comparison with the early resting echocardiographic study (1.72 +/- 0.29 vs 1.37 +/- 0.34, P <.001). In the remaining 25 patients (group II), no wall motion enhancement was seen at follow-vp (1.57 +/- 0.38 vs 1.58 +/- 0.36, NS). In 22 of the 24 patients in group I, early low-dose dobutamine echocardiography showed improvement in the wall motion score index compared with baseline resting measurements (1.72 +/- 0.29 vs 1.44 +/- 0.24, P <.001). The positive and negative predictive value of early low-dose dobutamine echocardiography to predict Functional recovery was 76% and 92%, respectively. Conclusion Predischarge low-dose dobutamine echocardiography is an accurate tool for detecting viable myocardium and predicting late left ventricular recovery after acute myocardial infarction treated with thrombolysis.
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页码:489 / 493
页数:5
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