Muscle weakness: Understanding the principles of myopathy and neuropathy in the critically ill patient and the management options

被引:12
|
作者
Angel Garcia-Martinez, Miguel [1 ]
Montejo Gonzalez, Juan Carlos [2 ]
Garcia-de-Lorenzo y Mateos, Abelardo [3 ]
Teijeira, Susana [4 ]
机构
[1] Hosp Univ Torrevieja, Dept Intens Care Med, Ctra Torrevieja San Miguel de Salinas S-N, Alicante 03186, Spain
[2] Hosp Univ 12 Octubre, Dept Intens Care Med, Av Cordoba S-N, Madrid 28041, Spain
[3] Hosp Univ La Paz Carlos III, Dept Intens Care Med, IdiPAZ, Paseo Castellana 261, Madrid 28046, Spain
[4] Complejo Hosp Univ Vigo, SERGAS UVIGO, Rare Dis & Pediat Med Res Grp, Galicia Sur Hlth Res Inst,IIS Galicia Sur, Calle Clara Campoamor 341, Vigo 36312, Pontevedra, Spain
关键词
Critical illness; Muscle weakness; Myopathy; Neuropathy; INTENSIVE-CARE-UNIT; HYDROXY-BETA-METHYLBUTYRATE; CRITICAL ILLNESS POLYNEUROPATHY; SKELETAL-MUSCLE; MECHANICAL VENTILATION; ACQUIRED WEAKNESS; BODY-COMPOSITION; COMPUTED-TOMOGRAPHY; NUTRITIONAL SUPPORT; PROTEIN-METABOLISM;
D O I
10.1016/j.clnu.2019.05.027
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Myo-neuropathy of the critically ill patient is a difficult nosological entity to understand and manage. It appears soon after injury, and it is estimated that 20-30% of patients admitted to Intensive Care Units will develop it in some degree. Although muscular and nervous involvement are related, the former has a better prognosis. Myo-neuropathy associates to more morbidity, longer stay in Intensive Care Unit and in hospital, and also to higher costs and mortality. It is considered part of the main determinants of the new entities: the Chronic Critical Patient and the Post Intensive Care Syndrome. This update focuses on aetiology, pathophysiology, diagnosis and strategies that can prevent, alleviate and/or improve muscle (or muscle-nerve) weakness. (C) 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
引用
收藏
页码:1331 / 1344
页数:14
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