Robust classification ensemble method for microarray data

被引:3
|
作者
Chung, Dongjun [2 ]
Kim, Hyunjoong [1 ]
机构
[1] Yonsei Univ, Dept Appl Stat, Seoul 120749, South Korea
[2] Univ Wisconsin, Dept Stat, Madison, WI 53706 USA
基金
新加坡国家研究基金会;
关键词
classification; ensemble; microarray data; robustness; data mining; bioinformatics; decision trees; EXPRESSION; PREDICTION; CANCER; TUMOR;
D O I
10.1504/IJDMB.2011.043032
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The objective of this study is to develop an accurate and robust classification ensemble method suitable for microarray data with noises. We proposed an algorithm, pattern match (PM)-bagging, which performs well in accuracy and is robust to noise variables and noise observations. From the experiments with real data set, the performance of the proposed method is found quite comparable and not much degraded even when the data set has noise variables or noise observations, while some other ensemble methods showed degradations of performance. A bias and variance decomposition showed that the success of the proposed method is due to an effective reduction of both bias and variance.
引用
收藏
页码:504 / 518
页数:15
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