Meta-Analysis of Dyslipidemia and Blood Lipid Parameters on the Risk of Primary Open-Angle Glaucoma

被引：3
|
作者：
Huang, Guimei [1 ]
Wang, Jiayi [2 ]
Li, Lei [3 ]
Gao, Yuan [3 ]
Yan, Yijie [3 ]
机构：
[1] Qionghai Peoples Hosp, Ophthalmol Dept, Hainan 571400, Qionghai, Peoples R China
[2] Qionghai Jianping Hosp, Ophthalmol Dept, Hainan 571400, Qionghai, Peoples R China
[3] Hainan Med Univ, Hainan Gen Hosp, Ophthalmol Dept, Hainan Affiliated Hosp, Haikou 570311, Hainan, Peoples R China
来源：
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE | 2022年 / 2022卷
关键词：
KOREA-NATIONAL-HEALTH; INTRAOCULAR-PRESSURE; POPULATION; PREVALENCE; HYPOTHYROIDISM;
D O I：
10.1155/2022/1122994
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Objective. We aimed to explore the effect of blood lipid parameters on the risk of primary open-angle glaucoma (POAG) by meta-analysis. Methods. The databases of PubMed, Scopus, CNKI, and Wanfang were systematically searched from inception to April 2022, and the relevant research literature was obtained, screened, and analyzed. Results. A total of 15 studies were included in this meta-analysis, including 11 reporting dyslipidemia and risk of POAG and 5 reporting specific lipid level and risk of POAG. Dyslipidemia increased the risk of POAG with an odd ratio (OR) of 1.25 (95% CI: 1.23, 1.26). Total triglyceride and total cholesterol were not related to the prevalence of POAG, but high-density lipoprotein cholesterol was significantly negatively correlated with the risk of POAG with an OR of 0.96 (95% CI: 0.94, 0.99). Conclusion. Dyslipidemia is a risk factor for POAG. Given the small sample size and significant interstudy heterogeneity, additional studies are needed to establish this conclusion.
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页数：8
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