The Grignard reagent from 2-bromomethyl-1,3-dioxolane, a novel and efficient d(2)-reagent: Synthesis of branched chain carbohydrate derivatives

被引：0

作者：

Schmeichel, M ^{[1
]}

Redlich, H ^{[1
]}

机构：

[1] UNIV MUNSTER,INST ORGAN CHEM,D-48149 MUNSTER,GERMANY

来源：

SYNTHESIS-STUTTGART | 1996年 / 08期

关键词：

2-bromomethyl-1,3-dioxolane; Grignard reagent; magnesium; d(2)-synthon; carbohydrate ketones;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Bromomethyl-1,3-dioxolane reacts readily with magnesium in tetrahydrofuran to form the corresponding Grignard reagent, which ;can be used as a novel and efficient d(2)-synthon in organic synthesis. The unusual stability of this reagent even allows the addition to unreactive carbohydrate ketones at elevated temperatures.

引用

页码：1002 / &

页数：6

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