Cannabinoids and sleep-wake cycle: The potential role of serotonin

被引：11

作者：

Vaseghi, Salar ^{[1
,2
]}

Arjmandi-Rad, Shirin ^{[3
]}

Nasehi, Mohammad ^{[1
]}

Zarrindast, Mohammad-Reza ^{[2
,4
]}

机构：

[1] Islamic Azad Univ, Amir Almomenin Hosp, Cognit & Neurosci Res Ctr CNRC, Tehran Med Sci, POB 13145-784, Tehran, Iran

[2] Inst Cognit Sci Studies ICSS, Dept Cognit Neurosci, Tehran, Iran

[3] Shahid Beheshti Univ, Inst Cognit & Brain Sci, Tehran, Iran

[4] Univ Tehran Med Sci, Dept Pharmacol, Sch Med, Tehran, Iran

来源：

BEHAVIOURAL BRAIN RESEARCH | 2021年 / 412卷

关键词：

Cannabinoid; Serotonin; Sleep; Waking; DORSAL RAPHE NUCLEUS; EYE-MOVEMENT SLEEP; ENHANCES EXTRACELLULAR LEVELS; CB1 RECEPTOR ANTAGONIST; SUPPRESSES REM-SLEEP; ACID AMIDE HYDROLASE; C-FOS EXPRESSION; LATERAL HYPOTHALAMUS; MODULATES SLEEP; PREFRONTAL CORTEX;

D O I：

10.1016/j.bbr.2021.113440

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Cannabis sativa (Marijuana) has a long history as a medicinal plant and Delta 9-tetrahydrocannabinol (Delta 9-THC) is the most active component in this plant. Cannabinoids are interesting compounds with various modulatory effects on physiological processes and cognitive functions. The use of cannabinoids is a double-edged sword, because they induce both adverse and therapeutic properties. One of the most important roles of cannabinoids is modulating sleep-wake cycle. Sleep, its cycle, and its mechanism are highly unknown. Also, the effects of cannabinoids on sleep-wake cycle are so inconsistent. Thus, understanding the role of cannabinoids in modulating sleep-wake cycle is a critical scientific goal. Cannabinoids interact with many neurotransmitter systems. In this review article, we chose serotonin due to its important role in regulating sleep-wake cycle. We found that the interaction between cannabinoids and serotonergic signaling especially in the dorsal raphe is extensive, unknown, and controversial.

引用

页数：10

共 50 条

[1] The Role of Neuroglobin in the Sleep-Wake Cycle
Garcia-Garcia, Fabio
Acosta-Hernandez, Mario Eduardo
Beltran-Parrazal, Luis
Rodriguez-Alba, Juan Carlos
[J]. SLEEP SCIENCE, 2023, 16 (03) : E362 - E367
[2] Role of Thalamus in Sleep-Wake Cycle Regulation
Guaraldi, Pietro
Calandra-Buonaura, Giovanna
Provini, Federica
Cortelli, Pietro
[J]. ANNALS OF NEUROLOGY, 2019, 85 (04) : 611 - 611
[3] Tau Protein Role in Sleep-Wake Cycle
Cantero, Jose L.
Hita-Yanez, Eva
Moreno-Lopez, Bernardo
Portillo, Federico
Rubio, Alicia
Avila, Jesus
[J]. JOURNAL OF ALZHEIMERS DISEASE, 2010, 21 (02) : 411 - 421
[4] Stimulants and Depressor Drugs in the Sleep-wake Cycle Modulation: The Case of Alcohol and Cannabinoids
Murillo-Rodriguez, Eric
Carreon, Cristina
Eduardo Acosta-Hernandez, Mario
Garcia-Garcia, Fabio
[J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2022, 22 (15) : 1270 - 1279
[5] The Role of the Sleep-Wake Cycle in Adolescent Mental Illness
Wilson, Chloe
Carpenter, Joanne
Hickie, Ian
[J]. CURRENT SLEEP MEDICINE REPORTS, 2019, 5 (03) : 118 - 127
[6] Reply to "Role of Thalamus in Sleep-Wake Cycle Regulation"
Geerling, Joel C.
Boes, Aaron D.
[J]. ANNALS OF NEUROLOGY, 2019, 85 (04) : 612 - 613
[7] The Role of the Sleep-Wake Cycle in Adolescent Mental Illness
Chloe Wilson
Joanne Carpenter
Ian Hickie
[J]. Current Sleep Medicine Reports, 2019, 5 : 118 - 127
[8] Melatonin and the sleep-wake cycle
Kunz, D.
[J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2008, 18 : S597 - S597
[9] Serotonin control of sleep-wake behavior
Monti, Jaime M.
[J]. SLEEP MEDICINE REVIEWS, 2011, 15 (04) : 269 - 281
[10] Migraine and "sleep-wake" cycle
Osipova, V. V.
Levin, Ya. I.
[J]. ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA, 2006, 106 (05) : 9 - 15

← 1 2 3 4 5 →