A one-pot method for the efficient preparation of aromatic nitriles from aldehydes using ammonia, magnesium sulfate, and manganese dioxide

被引：0
|
作者：
Lai, GF [1 ]
Bhamare, NK [1 ]
Anderson, WK [1 ]
机构：
[1] SUNY Buffalo, Sch Pharm, Dept Med Chem, Buffalo, NY 14260 USA
来源：
SYNLETT | 2001年 / 02期
关键词：
aromatic nitriles; aldehydes; manganese dioxide;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot and efficient preparation of aromatic nitriles from the corresponding aldehydes was accomplished by treatment with 2 M ammonia solution in 2-propanol, magnesium sulfate, and manganese dioxide in THF at room temperature. This method was found to be compatible with a variety of functionalities such as hydroxyl, ester, and amide.
引用
收藏
页码：230 / 231
页数：2
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