A Serotonin Transporter Gene Promoter Polymorphism (5-HTTLPR), Serotonin 2C Receptor (5-HT2CR) and Sensation Seeking

被引:1
|
作者
Egorova, M. S. [1 ]
Alfimova, M. V. [2 ]
Parshikova, O. V. [1 ]
Pyankova, S. D. [1 ]
机构
[1] Moscow MV Lomonosov State Univ, Dept Psychol, Moscow 125009, Russia
[2] Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow 115522, Russia
关键词
Sensation seeking; Personality; Serotonin transporter polymorphism; Serotonin transporter receptor polymorphism; IMPULSIVITY; TRAITS; FAMILY; TWIN;
D O I
10.1016/j.sbspro.2013.08.519
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Association between different sensation seeking traits and related phenotypes with a serotonin transporter gene promoter polymorphism (5-HTTLPR) and serotonin 2C receptor (5-HT2CR) was studied in the male sample (university students, 16-26 years old). Sensation seeking traits correlated with Big 3 personality traits (Extraversion, Psychoticism, Neuroticism) and temperament traits (Novelty seeking and Harm avoidance). Polymorphism of 5-HTTLPR did not account for individual differences in personality traits but was associated with variation in Thrill and Adventure Seeking for everyday activities. Polymorphism of 5-HT2CR was related to individual differences in Boredom Susceptibility. (C) 2013 The Authors. Published by Elsevier Ltd.
引用
收藏
页码:24 / 28
页数:5
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