NONMELANOMA SKIN CANCER IN A HEART TRANSPLANT PATIENT: A CASE REPORT AND REVIEW OF THE LITERATURE

被引:1
|
作者
Rudez, Lorena Karla [1 ]
Sklebar, Tin [1 ]
Ceovic, Romana [1 ,2 ]
机构
[1] Univ Zagreb, Sch Med, Zagreb, Croatia
[2] Zagreb Univ Hosp Ctr, Dept Dermatovenereol, Kispaticeva 12, HR-10000 Zagreb, Croatia
关键词
Skin cancer; Heart transplantation; Immunosuppressants; Radiotherapy; SQUAMOUS-CELL CARCINOMA; SOLID-ORGAN TRANSPLANTATION; RISK-FACTORS; DERMATOLOGICAL COMPLICATIONS; IMMUNOSUPPRESSIVE THERAPY; KIDNEY-TRANSPLANTATION; MYCOPHENOLATE-MOFETIL; CALCINEURIN INHIBITOR; NATIONWIDE COHORT; IMMUNE-SYSTEM;
D O I
10.20471/acc.2022.61.01.21
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Nonmelanoma skin cancers (NMSC) are the most common malignancies in solid organ transplant recipients. The most common types of skin cancer in these patients are squamous cell carcinoma (SCC), followed by basal cell carcinoma. In immunosuppressed patients, specifically patients after solid organ transplantation, these carcinomas tend to be more aggressive and have a much higher incidence of metastasizing compared to general population. We present a case of a patient who developed numerous SCCs after successful heart transplantation. SCCs which occurred in our patient were mostly treated surgically. However, the lesion on the scalp relapsed after it had been treated surgically three times and therefore superficial x-ray radiation therapy was administered due to its localization and extensive size. In the next year, five more new SCCs occurred throughout the patient's body and all of them were removed surgically. Soon afterwards, the patient died from adenocarcinoma of the colon which rapidly progressed and metastasized.
引用
收藏
页码:157 / 165
页数:9
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