Distinct pharmacodynamics of insulin glargine and insulin detemir: Crossover comparison in Type 1 and Type 2 diabetic patients on basal-bolus regimen

被引：7

作者：

Kato, Tomoko ^{[1
]}

Tokubuchi, Ichiro ^{[1
]}

Muraishi, Kazuhisa ^{[1
]}

Sato, Shuichi ^{[1
]}

Kato, Tamotsu ^{[1
]}

Hara, Kento ^{[1
]}

Tanaka, Kayo ^{[1
]}

Kaku, Hiroo ^{[1
]}

Tajiri, Yuji ^{[1
]}

Yamada, Kentaro ^{[1
]}

机构：

[1] Kurume Univ, Sch Med, Dept Med, Div Endocrinol & Metab, Fukuoka 8300011, Japan

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2010年 / 90卷 / 03期

关键词：

Insulin glargine; Insulin detemir; Insulin lispro; Blood glucose; Pharmacodynamics; Crossover study; DOUBLE-BLIND;

D O I：

10.1016/j.diabres.2010.08.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We compared blood glucose profile when glargine or detemir was injected once daily before dinner in combination with pre-meal insulin lispro by a crossover design. Glargine showed lower post-dinner and bedtime glucose levels in Type 1 diabetes, and lower pre-dinner and post-dinner glucose levels in Type 2 diabetes than detemir. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E64 / E66

页数：3

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