Differential and tissue-specific expression of mitochondrial elongation factor Tu and Ts during development

被引：0

作者：

Chen, L ^{[1
]}

Xu, Q ^{[1
]}

Liu, XL ^{[1
]}

Zhao, J ^{[1
]}

Ma, L ^{[1
]}

机构：

[1] Shanghai Med Univ, State Key Lab Med Neurobiol, Shanghai 200032, Peoples R China

来源：

ACTA BIOCHIMICA ET BIOPHYSICA SINICA | 1999年 / 31卷 / 01期

关键词：

mitochondrial elongation factor Tu and Ts; gene expression;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mitochondrial elongation factors Tu and Ts (EF-Tu(mt)) and EF-Ts-mt are nuclear gene-encoded mitochondrial proteins and play important roles in growth and development, We prepared antibodies against EF-Tu(mt) and EF-Ts-mt using purified recombinant EF-Tu(mt) and EF-Ts-mt. Western analysis indicates EF-Tu(mt) and EF-Ts-mt are expressed differently in various tissues. Their expression in heart and liver increased during development and reached plateau at maturation. Expression of EF-Tu(mt) and EF-Ts-mt exhi-bited similar tissue-specificity and changed synchronically during development. These results suggest that expression levels of EF-Tu(mt) and EF-Ts-mt may be regulated by a similar mechanism related to the metabolic state of the cells.

引用

页码：37 / 40

页数：4

共 7 条

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