Biological immunoassay utilizing magnetic marker and high Tc superconducting quantum interference device magnetometer

被引：36
|
作者：
Enpuku, K
Kuroda, D
Ohba, A
Yang, TQ
Yoshinaga, K
Nakahara, T
Kuma, H
Hamasaki, N
机构：
[1] Kyushu Univ, Res Inst Superconductor Sci & Syst, Higashi Ku, Fukuoka 8128581, Japan
[2] Kyushu Inst Technol, Dept Appl Chem, Tobata Ku, Kitakyushu, Fukuoka 8048550, Japan
[3] Kyushu Univ, Dept Med Sci, Higashi Ku, Fukuoka 8128582, Japan
来源：
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS | 2003年 / 42卷 / 12A期
关键词：
SQUID magnetometer; immunoassay; antigen-antibody reaction; magnetic marker; remanence;
D O I：
10.1143/JJAP.42.L1436
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Detection of the biological binding-reaction between an antigen andits antibody was performed by using a magnetic marker and a high T-c superconducting quantum interference device (SQUID) magnetometer. In this method, the binding reaction is detected by measuring the magnetic field from the marker. A new marker made of Fe3O4 particle with diameter of 25 nm was developed, and the remanent field of the marker was used for the detection of the antigen called Interleukin 8 (IL8). It was shown that the present system can detect 0.1 pg weight of IL8.
引用
收藏
页码：L1436 / L1438
页数：3
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