Objective: To review the current research of new emerging diagnostic technology for non-invasive physiological monitoring of exercise and fitness. As a personal trainer, I believe that exercise can improve the conditions of several diseases and/or events such as stroke, post-traumatic head injury, spinal cord injury, and a multitude of other diseases. This compilation of information will allow health care providers tools of a non-invasive manner to promote healing and health that go beyond the initial event. Allowing patients continued managed care beyond what is believed to be their plateau. Material and method: Review science-based research involving non-invasive technology, including cardiovascular evaluations: heart rate monitors, near-infrared spectroscopy, blood pressure, and electrocardiography; motor capabilities: surface electromyography and manual testers, i.e. dynamometer, and digital and video photography; radiological monitoring: magnetic resonance imaging, three-dimensional computer tomography, and laser Doppler. Results: This investigation has found that a new approach should be implemented for non-invasive physiological monitoring of exercise and fitness through development and utilization across a wide variety of equipment, and monitoring technology. This non-invasive methodology will not only motivate but encourage individuals to begin and remain compliant with an exercise program allowing a variety of health care providers to assist in patient care. Discussion: We need to shift the paradigm from taking care of the sick to maintaining the health of our patients. This can be accomplished with non-invasive evaluation, tracking, and monitoring tools. Many of the suggestions for monitoring are used in a clinical setting rather than a general fitness environment. These monitoring tests need to be economical as well as available for continual re-evaluation.