Liposarcoma: Comparison of flow cytometric and image cytophotometric DNA measurements

被引：0
|
作者：
Neuburger, M [1 ]
Herget, GW [1 ]
Adler, CP [1 ]
机构：
[1] UNIV FREIBURG,INST PATHOL,REFERENZZENTRUM KNOCHENTUMOREN,D-79002 FREIBURG,GERMANY
来源：
ONCOLOGY REPORTS | 1996年 / 3卷 / 03期
关键词：
liposarcoma; image cytophotometry; flowcytometry; prognosis;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Using nuclear suspensions, the DNA-content of 7 bone-associated, paraffin-embedded liposarcomas and 3 lipomas were examined by means of flow cytometry (FCM) and was compared with the results of image cytophotometric measurements (ICM). Using ICM, 6 of 7 liposarcomas showed an aneuploid DNA content (86%), whereas FCM showed aneuploidy in 3 cases (43%). None of the lipomas had an aneuploid DNA-content using either method. The correspondance of the two methods was 70%. Because aneuploidy is of prognostic importance, ICM could be the method to determine the DNA content of liposarcoma.
引用
收藏
页码：559 / 562
页数：4
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