Lipoprotein(a) as a marker for predicting coronary collateral circulation in patients with acute myocardial infarction

被引：8
|
作者：
You, Xiang-Dong [1 ,2 ]
Jin, Jing-Lu [1 ]
Zhang, Hua [2 ]
Guo, Na [2 ]
Hou, Bing-Jie [2 ]
Guo, Yuan-Lin [1 ]
Wu, Na-Qiong [1 ]
Zhu, Cheng-Gang [1 ]
Li, Jian-Jun [1 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll, Natl Ctr Cardiovasc Dis, Fuwai Hosp, Div Dyslipidemia,State Key Lab Cardiovasc Med, Beijing 100037, Peoples R China
[2] Peoples Hosp Tangxian Cty, Dept Cardiol, Tangxian, Hebei, Peoples R China
来源：
PERSONALIZED MEDICINE | 2020年 / 17卷 / 01期
关键词：
acute myocardial infarction; collateral circulation; coronary artery; Lipoprotein(a); marker; prediction; ARTERY-DISEASE; RISK; ASSOCIATION; ANGIOPLASTY; BALLOON; IMPACT; LEVEL;
D O I：
10.2217/pme-2018-0127
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Aim: The aim of the present study was to examine the predictive value of lipoprotein(a) (Lp[a]) levels for coronary collateral circulation (CCC) in patients with acute myocardial infarction (AMI). Method & methods: A total of 409 consecutive patients with AMI were enrolled for this study. Patients were divided into two groups according to rentrop grades assessed by coronary angiography: bad (n = 277) and good CCC group (n = 132). Result: Patients with bad CCC had a higher level of Lp(a) than that with good CCC (median Lp[a] 219.1 vs 122.0 mg/l). The area under the receiver-operating characteristic curves of Lp(a) in predicting bad CCC was 0.647 (95% CI: 0.592-0.702) with the cut-off value of 199.0 mg/l. Conclusion: Our data firstly suggested that Lp(a) might be a useful marker for CCC after AMI.
引用
收藏
页码：67 / 78
页数：12
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