High-resolution genomic analysis: the tumor-immune interface comes into focus

被引：4
|
作者：
Havel, Jonathan J. [1 ]
Chan, Timothy A. [1 ,2 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, New York, NY 10065 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, New York, NY 10065 USA
来源：
GENOME BIOLOGY | 2015年 / 16卷
关键词：
CELLS; CANCER;
D O I：
10.1186/s13059-015-0631-3
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines.
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页数：3
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