The role of brain glucose metabolism in the development of cognitive dysfunctions in patients with remitting and secondary-progressive multiple sclerosis

被引：0
|
作者：
Shkilnuk, G. G. [1 ]
Ilves, A. G. [1 ]
Kataeva, G. V. [1 ]
Prakhova, L. N. [1 ]
Reznikova, T. N. [1 ]
Seliverstova, N. A. [1 ]
Stolyarov, I. D. [1 ]
机构：
[1] Russian Acad Sci, Inst Human Brain, St Petersburg 196140, Russia
来源：
ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA | 2012年 / 112卷 / 02期
关键词：
multiple sclerosis; cognitive impairment; PET; MEMORY IMPAIRMENT; ATROPHY; ACTIVATIONS;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
To study mechanisms of development of cognitive dysfunctions in multiple sclerosis (MS), brain glucose metabolism has been investigated using PET method. We have studied 61 patients with different types of MS course. Correlations between cognitive dysfunctions and regional glucose metabolic rate were revealed. The authors suggest that metabolic dysfunctions of the grey matter play the important role in the pathogenesis of cognitive disturbances in MS.
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页码：41 / 46
页数：6
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