HLA-A, -B,-DRB1 and-DQB1 polymorphisms among Iraqi Arabs

被引：3
|
作者：
Ad'hiah, Ali H. [1 ]
Al-rikabi, Aaiad H. [2 ]
Ahmed, Zahra'a A. [3 ]
Kamil, Liath A. [4 ]
机构：
[1] Univ Baghdad, Coll Sci, Trop Biol Res Unit, Baghdad, Iraq
[2] Univ Baghdad, Dept Biol, Coll Sci, Baghdad, Iraq
[3] Univ Baghdad, Dept Biol, Coll Sci Women, Baghdad, Iraq
[4] Minist Hlth, Al Karama Teaching Hosp, Histocompatibil Ctr, Baghdad, Iraq
来源：
HUMAN IMMUNOLOGY | 2020年 / 81卷 / 05期
关键词：
Iraqi Arabs; HLA; Polymorphism; Allele frequency; Haplotype;
D O I：
10.1016/j.humimm.2020.03.006
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this report, HLA polymorphisms (A, B, DRB1 and DQB1 loci) were determined in 149 unrelated Iraqi Arab potential bone marrow and kidney donors. Molecular genotyping was carried out by polymerase chain reaction followed by specific oligonucleotide probe hybridizations. Data were analyzed by Arlequin software. HLA-A, -B and -DRB1 genotype frequencies were significantly deviated from Hardy-Weinberg equilibrium, while HLADQB1 frequencies showed no deviation. A*03, B*35, DRB1*11 and DQB1*02 were the most frequent allele groups, while A*02-B*07-DRB1*04-DQB1*03 was the most frequent haplotype. HLA data are available in the Allele Frequencies Net Database (AFND: 3680) under the population name "Iraq Arabs".
引用
收藏
页码：191 / 192
页数：2
相关论文
共 50 条
  • [1] Study of HLA-A,-B,-C,-DRB1 and-DQB1 polymorphisms in COVID-19 patients
    Gutierrez-Bautista, Juan Francisco
    Rodriguez-Nicolas, Antonio
    Rosales-Castillo, Antonio
    Lopez-Ruz, Miguel Angel
    Martin-Casares, Antonia Maria
    Fernandez-Rubiales, Alonso
    Anderson, Per
    Garrido, Federico
    Ruiz-Cabello, Francisco
    Lopez-Nevot, Miguel Angel
    [J]. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2022, 55 (03) : 421 - 427
  • [2] HLA-A, -B, -C,-DRB1 and-DQB1 allele and haplotype frequencies in the Serbian population
    Andric, Zorana
    Popadic, Dusan
    Jovanovic, Barbara
    Jaglicic, Ivana
    Bojic, Svetlana
    Simonovic, Ruzica
    [J]. HUMAN IMMUNOLOGY, 2014, 75 (03) : 218 - 226
  • [3] Evaluation of LabType-SSO HLA Typing for HLA-A, -B, -C,-DRB1, and-DQB1 loci
    Nam, Minjeong
    Jung, Kiwook
    Roh, Eun Youn
    Shin, Sue
    Park, Kyoung Un
    Song, Eun Young
    [J]. CLINICAL LABORATORY, 2021, 67 (01) : 208 - 212
  • [4] Distribution of HLA-A, -C, -B,-DRB1, and-DQB1 polymorphisms in the Korean minority in Kazakhstan, and relatedness to neighboring and distant populations
    Almawi, Wassim Y.
    Hajjej, Abdelhafidh
    Abdrakhmanova, Saniya
    Turganbekova, Aida
    [J]. GENE, 2022, 823
  • [5] DISTRIBUTION OF HLA-A, -B, -C,-DRB1 AND-DQB1*ALLELES AND HAPLOTYPES AMONG DIFFERENT SOUTH INDIAN POPULATION
    Vani, Seshasubramanian
    Devi, SathishKannan Aruna
    Chandramouleeswaran, Naganathan
    Yogesh, Nanda Kumar
    Srinivasan, Periathiruvadi
    Saranya, Narayan
    [J]. HLA, 2019, 93 (05) : 337 - 338
  • [6] HLA-A, -B, -C,-DRB1 AND-DQB1 ALLELE FREQUENCIES OF THE NATIONAL REGISTER OF THE REPUBLIC OF KAZAKHSTAN
    Turganbekova, Aida
    Zhanzakova, Zhuldyz
    Parkhomenko, Irina
    Saduakas, Zhazira
    Komarova, Damira
    Siyazbek, Assel
    Abdrakhmanova, Saniya
    Omarov, Rustem
    [J]. HLA, 2021, 97 (04) : 326 - 326
  • [7] HLA-A, -B,-DRB1,-DQA1, and-DQB1 profile in a population from southern Brazil
    Reis, Pamela G.
    Ambrosio-Albuquerque, Eliane P.
    Fabreti-Oliveira, Raquel A.
    Moliterno, Ricardo A.
    de Souza, Victor H.
    Sell, Ana M.
    Visentainer, Jeane E. L.
    [J]. HLA, 2018, 92 (05) : 298 - 303
  • [8] HLA-A, -B, -C,-DRB1 and-DQB1 allele and haplotype frequencies and phylogenetic analysis of Bahraini population
    Hajjej, Abdelhafidh
    Saldhana, F. Lisa
    Dajani, Rana
    Almawi, Wassim Y.
    [J]. GENE, 2020, 735
  • [9] HLA-A, -B,-DRB1,-DQA1, and-DQB1 genotyping of 641 individuals from southern Brazil
    Lima Vendramini, Evelyn Castillo
    de Lima Neto, Quirino Alves
    Reis, Pamela Guimaraes
    Moliterno, Ricardo Alberto
    de Souza, Victor Hugo
    Sell, Ana Maria
    Laguila Visentainer, Jeane Eliete
    [J]. HUMAN IMMUNOLOGY, 2020, 81 (01) : 8 - 9
  • [10] THE IMMPUTE PROJECT: EVALUATING SNP IMPUTATION METHODOLOGIES FOR HLA-A, -B, -C,-DRB1 AND-DQB1 GENOTYPES
    Pappas, Derek
    Paunic, Vanja
    Lizee, Antoine M.
    Taylor, Kent
    Leslie, Stephen
    Meller, Jarek
    Zheng, Xiuwen
    Zhao, Lue Ping
    Gourraud, Pierre-Antoine
    Hollenbach, Jill A.
    Maiers, Martin
    Mack, Steven J.
    [J]. TISSUE ANTIGENS, 2014, 84 (01): : 12 - 13
12345