Spectrum of kidney disease, a ten years' experience of renal biopsies at single center tertiary care hospital

Objective: To determine the frequency with type of renal diseases by renal biopsy at our center. Methodology: This petrospective study of renal biopsies was performed at Department of Nephrology JPMC, Karachi from January 2009 to May 2019. We categorized the patients according to age, gender. We have light microscopy and immunofluorescence examination only. Results: A total of 502 renal biopsies were performed. There were 207 male and 199 female patients. In the glomerular lesions, most common was FSGS of 30.5% and Membranous GN of 15.3 % followed by MPGN of 9.4%, Lupus Nephritis 15.3%, vasculitis 2.2%, Chronic Sclerosing GN 2%, ATN 8.6%, AIN 0.2% and others of 14.5%. Conclusion: Our 10 years biopsy data analysis showed Nephritic Syndrome as the most common clinical indication for biopsy and FSGS is the leading lesion with 30.5% cases.