Homologous recombination deficiency (HRD) scoring in pancreatic ductal adenocarcinoma (PDAC) and response to chemotherapy

被引：0
|
作者：
O'Kane, Grainne M.
Denroche, Rob
Picardo, Sarah Louise
Zhang, Amy
Holter, Spring
Grant, Robert C.
Allen, Michael
Wang, Yifan
Dodd, Anna
Ramotar, Stephanie
Hutchinson, Shawn
Tehfe, Mustapha
Biagi, James Joseph
Wilson, Julie
Notta, Faiyaz
Fischer, Sandra
Zogopoulos, George
Gallinger, Steven
Knox, Jennifer J.
机构：
[1] Princess Margaret Canc Ctr, Toronto, ON, Canada
[2] Ontario Inst Canc Res, Toronto, ON, Canada
[3] Beaumont Hosp, Dept Med Oncol, Dublin, Ireland
[4] Ontario Inst Canc Res, Toronto, ON, Canada
[5] Samuel Lunenfeld Res Inst, Toronto, ON, Canada
[6] Princess Margaret Canc Ctr, Div Med Oncol & Hematol, Toronto, ON, Canada
[7] McGill Univ, Montreal, PQ, Canada
[8] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada
[9] CHU Montreal, Hop Notre Dame, Montreal, PQ, Canada
[10] Queens Univ, Canc Ctr Southeastern Ontario, Kingston, ON, Canada
[11] Univ Hlth Network, Toronto Gen Hosp, Toronto, ON, Canada
[12] McGill Univ, Hlth Ctr, Montreal, PQ, Canada
[13] Toronto Gen Hosp, Toronto, ON, Canada
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2020年 / 38卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
741
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Efficacy of olaparib therapy in metastatic pancreatic ductal adenocarcinoma (PDAC) with homologous recombination deficiency (HRD).
    Tan, Elaine
    Hicks, James Kevin
    Blue, Kirsten
    Kim, Richard D.
    Carballido, Estrella M.
    Kim, Dae Won
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [2] P-PROFILER: refining criteria for homologous recombination deficiency (HRD) in pancreatic ductal adenocarcinoma (PDAC)
    Pfarr, N.
    Kling, C.
    Koppermann, M.
    Mayr, E.
    Merkl, K.
    Jacob, A.
    Kwiatkowski, A. Terron
    Muckenhuber, A.
    Heiss, Q.
    Wagner, Y.
    Walker, M.
    Chakraborty, S.
    Schwamborn, K.
    Quante, M.
    Lange, S.
    VIRCHOWS ARCHIV, 2024, 485 : S135 - S136
  • [3] Homologous Recombination Deficiency in Patients With Pancreatic Ductal Adenocarcinoma and Response to Chemotherapy
    Shahda, Safi
    Timms, Kirsten M.
    Ibrahim, Ashley A.
    Reid, Julia E.
    Cramer, Harvey M.
    Radovich, Milan
    Ibrahim, Sulfikar
    Allen, Brian
    O'Neil, Bert H.
    JCO PRECISION ONCOLOGY, 2018, 2 : 1 - 11
  • [4] Homologous recombination deficiency (HRD) alterations as a predictor of responsiveness to combination pancreatic cancer in advanced pancreatic ductal adenocarcinoma (PDAC).
    Randall, Jamie
    Cannon, Timothy Lewis
    Wadlow, Raymond Couric
    Wang, Hongkun
    Winer, Arthur
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E16259 - E16259
  • [5] Identification of therapeutic vulnerabilities in the subset of pancreatic ductal adenocarcinoma (PDAC) with homologous recombination deficiency
    Tesson, Mathias
    Kong, Kay
    Repsicak, Peter
    Bader, Aldo
    Hsieh, Ya-Ching
    Nourse, Craig
    Kirschner, Kristina
    Miller, Crispin
    Roberts, Ed
    Chang, David
    Morton, Jen
    CANCER RESEARCH, 2024, 84 (17)
  • [6] Homologous recombination deficiency (HRD): A biomarker for first-line (1L) platinum in advanced pancreatic ductal adenocarcinoma (PDAC).
    Park, Wungki
    Wong, Winston
    Yu, Kenneth H.
    Varghese, Anna M.
    Riaz, Nadeem
    Balachandran, Vinod P.
    El Dika, Imane H.
    Raj, Nitya Prabhakar
    Khalil, Danny
    Ku, Geoffrey Yuyat
    Segal, Neil Howard
    Li, Jia
    Chalasani, Sree Bhavani
    Chong, Curtis Robert
    Kelsen, David Paul
    Abou-Alfa, Ghassan K.
    Berger, Michael F.
    Schultz, Nikolaus
    Iacobuzio-Donahue, Christine A.
    O'Reilly, Eileen Mary
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [7] Homologous recombination deficiency (HRD) in patients with pancreatic cancer (PC) and response to chemotherapy
    Shahda, Safi
    Timms, Kirsten
    Ibrahim, Ashley
    Reid, Julia E.
    Cramer, Harvey M.
    Radovich, Milan
    Ibrahim, Sulfikar
    Allen, Brian
    O'Neil, Bert H.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [8] Dynamic immunoediting by macrophages in homologous recombination deficiency-stratified pancreatic ductal adenocarcinoma
    Hong, Wei-Feng
    Zhang, Feng
    Wang, Nan
    Bi, Jun-Ming
    Zhang, Ding-Wen
    Wei, Lu-Sheng
    Song, Zhen-Tao
    Mills, Gordon B.
    Chen, Min-Min
    Li, Xue-Xin
    Du, Shi-Suo
    Yu, Min
    DRUG RESISTANCE UPDATES, 2024, 76
  • [9] Genetic algorithms to identify homologous recombination deficiency (HRD) in pancreas adenocarcinoma
    Park, Wungki
    Chen, Jiapeng
    Chou, Joanne F.
    Iacobuzio-Donague, Christine
    Riaz, Nadeem
    O'Reilly, Eileen M.
    CANCER RESEARCH, 2020, 80 (16)
  • [10] Oral cavity immune response in pancreatic ductal adenocarcinoma (PDAC)
    Marquez, J. P.
    Lucero-Diaz, P. A.
    Matute-Briseno, J. A.
    Rosas-Delgado, M. O.
    Camacho-Hernandez, A.
    Cortez-Vargas, Y.
    Nava-Sanchez, I.
    Montano, G. T.
    Montijo-Fernandez, L. N.
    Perez-Astorga, M. A.
    ANNALS OF ONCOLOGY, 2018, 29 : 44 - 44
12345