Enantioselective total synthesis of (+)-galbulin via organocatalytic domino Michael-Michael-aldol condensation

被引：35
|
作者：
Hong, Bor-Cherng [1 ]
Hsu, Che-Sheng [1 ]
Lee, Gene-Hsiang [2 ]
机构：
[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 621, Taiwan
[2] Natl Taiwan Univ, Instrumentat Ctr, Taipei 106, Taiwan
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 18期
关键词：
ASYMMETRIC-SYNTHESIS; CASCADE REACTIONS; NATURAL-PRODUCTS; LIGNANS; ANALOGS; EPIPODOPHYLLOTOXIN; STEREOCHEMISTRY; PODOPHYLLOTOXIN; (+/-)-GALBULIN; CHEMISTRY;
D O I：
10.1039/c2cc16682h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A concise and practical enantioselective synthesis of (+)-galbulin has been achieved using organocatalytic domino Michael-Michael-aldol condensation and organocatalytic kinetic resolution as the key steps.
引用
收藏
页码：2385 / 2387
页数：3
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