Interaction with HSP90 protects nitric oxide synthases from proteolytic degradation by calpain

被引:0
|
作者
Melloni, E. [1 ]
Averna, M. [1 ]
Stifanese, R. [1 ]
De Tullio, R. [1 ]
Salamino, F. [1 ]
Bertuccio, M. [1 ]
Pontremoli, S. [1 ]
机构
[1] Univ Genoa, DIMES, Biochem Sect, I-16132 Genoa, Italy
关键词
calcium dependent proteolysis; NO synthase isoenzymes; HSP90;
D O I
10.1016/j.yjmcc.2008.02.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2
引用
收藏
页码:711 / 712
页数:2
相关论文
共 50 条
  • [1] Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90
    Averna, Monica
    Stifanese, Roberto
    De Tullio, Roberta
    Salamino, Franca
    Bertuccio, Mara
    Pontremoli, Sandro
    Melloni, Edon
    [J]. FEBS JOURNAL, 2007, 274 (23) : 6116 - 6127
  • [2] In vivo degradation of nitric-oxide synthase isozymes by calpain is regulated by HSP90
    Melloni, E.
    Averna, M.
    Stifanese, R.
    De Tullio, R.
    Salamino, F.
    Pontremoli, S.
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 : S108 - S108
  • [3] In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS-HSP90 heterocomplex
    Averna, Monica
    Stifanese, Roberto
    De Tullio, Roberta
    Salamino, Franca
    Pontremoli, Sandro
    Melloni, Edon
    [J]. FEBS JOURNAL, 2008, 275 (10) : 2501 - 2511
  • [4] Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation
    Kim, TS
    Jang, CY
    Kim, HD
    Lee, JY
    Ahn, BY
    Kim, J
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2006, 17 (02) : 824 - 833
  • [5] Endothelial nitric oxide synthase (eNOS) degradation is regulated by HSP90 not by phosphorylation
    Chen, WG
    Chen, YR
    Cardounel, AJ
    Zweier, J
    [J]. CIRCULATION, 2005, 112 (17) : U269 - U269
  • [6] Just say NO: nitric oxide regulation of Hsp90
    Scroggins, Bradley T.
    Neckers, Len
    [J]. EMBO REPORTS, 2009, 10 (10) : 1093 - 1094
  • [7] Functional Role of HSP90 Complexes with Endothelial Nitric-oxide Synthase (eNOS) and Calpain on Nitric Oxide Generation in Endothelial Cells
    Averna, Monica
    Stifanese, Roberto
    De Tullio, Roberta
    Passalacqua, Mario
    Salamino, Franca
    Pontremoli, Sandro
    Melloni, Edon
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (43) : 29069 - 29076
  • [8] Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90
    Sud, Neetu
    Sharma, Shruti
    Wiseman, Dean A.
    Harmon, Cynthia
    Kumar, Sanjiv
    Venema, Richard C.
    Fineman, Jeffrey R.
    Black, Stephen M.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2007, 293 (06) : L1444 - L1453
  • [9] Dynamic activation of endothelial nitric oxide synthase by Hsp90
    Guillermo García-Cardeña
    Roger Fan
    Vijay Shah
    Raffaella Sorrentino
    Giuseppe Cirino
    Andreas Papapetropoulos
    William C. Sessa
    [J]. Nature, 1998, 392 : 821 - 824
  • [10] Nitric oxide is involved in Hsp90α translocation to the cell surface
    Lei, H
    Kazlauskas, A
    [J]. DIABETES, 2005, 54 : A559 - A559