Microwave-Assisted Biosynthesis of CuO Nanoparticles Using Atalantia monophylla (L.) Leaf Extract and its Biomedical Applications

被引:8
|
作者
Verma, Ravikant [1 ]
Khan, Anisa Basheer [1 ]
Khan, M. Imran K. [2 ]
Amar, Ashutosh Kumar [2 ]
Sah, Suresh [2 ]
Jaiswal, Krishna Kumar [3 ,4 ]
Singh, Ram Kishore [5 ]
机构
[1] Pondicherry Univ, Dept Ecol & Environm Sci, Pondicherry 605014, India
[2] Pondicherry Univ, Dept Biotechnol, Pondicherry 605014, India
[3] Uttaranchal Univ, Dept Chem, Dehra Dun 248007, Uttarakhand, India
[4] Durban Univ Technol, Inst Water & Wastewater Technol, ZA-4001 Durban, South Africa
[5] Cent Univ Jharkhand, Dept Nanosci & Technol, Jharkhand 835222, India
关键词
Anticancer activity; Atalantia monophylla; Copper oxide nanoparticles; Microwave-assisted biosynthesis; COPPER-OXIDE NANOPARTICLES; GREEN SYNTHESIS; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; SILVER NANOPARTICLES; ANTICANCER ACTIVITY; TIO2; NANOPARTICLES; ESCHERICHIA-COLI; ESSENTIAL OIL; L CORREA;
D O I
10.1002/ceat.202000529
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The facile and rapid biosynthesis of copper oxide nanoparticles (AM-CuONPs) using Atalantia monophylla leaves extract under microwave irradiation is investigated. Optical and structural characterizations confirm the synthesis of spherical to rod-shaped phase pure AM-CuONPs. The antibacterial activity of AM-CuONPs is higher with Gram-positive bacteria compared to Gram-negative bacteria. The antioxidant potential of AM-CuONPs is reflected in radical scavenging activities in a concentration-dependent manner, tested by 2,2-diphenyl-1-picrylhydrazyl and 3-ethylenebenzothiazoline-6-sulfonic acid diammonium salt assay. The promising anticancer activity of AM-CuONPs is observed by killing similar to 80% of HeLa cells without affecting normal human embryonic kidney cells. The results reveal the potential of biosynthesized AM-CuONPs for antibacterial, antioxidant, and anticancer applications.
引用
收藏
页码:1496 / 1503
页数:8
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