Evolution of the Concept of Biocompatibility and the Cardioprotective Effect of On-Line Hemodiafiltration

被引:0
|
作者
Ramirez, Rafael [1 ]
Martin-Malo, Alejandro [1 ]
Aljama, Pedro [1 ]
机构
[1] Univ Cordoba, Dept Nephrol, Hosp Reina Sofia, Cordoba, Spain
关键词
ENDOTHELIAL DAMAGE; HEMODIALYSIS-PATIENTS; MONONUCLEAR-CELLS; MICROINFLAMMATION; MONOCYTES; INFLAMMATION; APOPTOSIS; UREMIA; CD14;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Chronic inflammation presented by chronic kidney disease patients is accompanied by an increase in the percentage of CD14+/CD16+ monocytes. The inflammatory activity produced by these cells provokes the activation and death of endothelial cells, which suggests that these cells may play an important role in the coupling of inflammation and endothelial damage in these patients. Therefore, the reduction in CD14+/CD16+ inhibitory monocytes may constitute a therapeutic goal in the treatment of chronic kidney disease patients. The use of the most effective hemodialysis techniques such as on-line hemodiafiltration appears to be a suitable tool for achieving this objective. Copyright (C) 2011 S. Karger AG, Basel
引用
收藏
页码:110 / 116
页数:7
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