The importance of developing metal complexes with pronounced catalase-like activity

被引:35
|
作者
Mahammed, Atif [1 ]
Gross, Zeev [1 ]
机构
[1] Technion Israel Inst Technol, Schulich Fac Chem, IL-32000 Haifa, Israel
基金
以色列科学基金会;
关键词
HYDROGEN-PEROXIDE; SUPEROXIDE-DISMUTASE; REACTIVE OXYGEN; CYTOPROTECTIVE AGENTS; AMPHIPHILIC CORROLES; TYROSINE NITRATION; NITRIC-OXIDE; PEROXYNITRITE; DECOMPOSITION; PORPHYRINS;
D O I
10.1039/c1cy00063b
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This critical survey reveals that in contrast with the large advances in the development of synthetic catalysts for decomposition of superoxide anion radical and peroxynitrite, most metal complexes reported until recently perform very poor when it comes to disproportionation of hydrogen peroxide, the reaction catalyzed by enzymes of the catalase family.
引用
收藏
页码:535 / 540
页数:6
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