Granulomatous hepatitis after intravesical bacillus Calmette-Guerin treatment

被引:6
|
作者
Adami, Maddalena [1 ]
Marsteller, Igor [1 ]
Mazzucchelli, Luca [2 ]
Cerny, Andreas [3 ]
Bernasconi, Enos [1 ]
机构
[1] Osped Reg Lugano, Dipartimento Med Interna, Lugano, Switzerland
[2] Ist Cantonale Patol, Locarno, Switzerland
[3] Clin Luganese Moncucco Lugano, Lugano, Switzerland
关键词
SUPERFICIAL BLADDER-CANCER; CARCINOMA; IMMUNOTHERAPY; INSTILLATION; INFECTION; THERAPY;
D O I
10.3109/00365548.2010.515609
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A 79-y-old man presented with systemic inflammatory response syndrome (SIRS) and jaundice, 6 h after the first intravesical instillation of bacillus Calmette-Guerin (BCG) for bladder cancer; he had a subsequent reaction 4 weeks later. Liver biopsy findings were compatible with BCG hepatitis. Anti-mycobacterial treatment induced complete recovery. The first episode probably represents a hypersensitivity reaction, whereas the latter course suggests BCG dissemination.
引用
收藏
页码:55 / 57
页数:3
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