Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?

被引:4
|
作者
Merchant, Hamid A. [1 ]
机构
[1] Univ Huddersfield, Sch Appl Sci, Dept Pharm, Huddersfield HD1 3DH, W Yorkshire, England
关键词
diabetes risk; insulin resistance; fatty liver disease; hyperinsulinemia; NAFLD; NASH; intensive lifestyle change program; WEIGHT-LOSS; PHYSICAL-ACTIVITY;
D O I
10.3390/jcm6090088
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Subjects diagnosed with non-alcoholic fatty liver disease (NAFLD) or hepatic steatosis are usually obese or overweight. NAFLD has also been reported in many non-obese healthy subjects as an incidental finding during imaging. Subjects with early-stage NAFLD who are otherwise healthy are often left unmanaged in current clinical practice; it is not clear if an early intervention in those individuals would be of any benefit in preventing NAFLD progression to more serious conditions. Since many of these subjects are non-alcoholic and have a normal body mass index (BMI), an intensive lifestyle change program is not usually recommended. This report presents an otherwise healthy non-alcoholic subject with incidental NAFLD having a normal BMI and a waist circumference below 90 cm who successfully reversed his condition by undertaking a lifestyle intervention. The case report is expected to encourage large cohort studies to substantiate the benefits of dietary interventions in alleviating hepatic steatosis among non-obese individuals.
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页数:5
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