The Biomarkers for Acute Myocardial Infarction and Heart Failure

被引:92
|
作者
Wang, Xi-Ying [1 ]
Zhang, Fen [1 ]
Zhang, Chi [1 ]
Zheng, Liang-Rong [1 ]
Yang, Jian [1 ]
机构
[1] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Dept Cardiol, Hangzhou, Peoples R China
关键词
SENSITIVITY-CARDIAC TROPONIN; ACUTE CORONARY SYNDROME; DIFFERENTIATION FACTOR 15; SOLUBLE CD40 LIGAND; LONG NONCODING RNA; PLASMA-PROTEIN-A; VENTRICULAR SYSTOLIC DYSFUNCTION; MEAN PLATELET VOLUME; ACID-BINDING PROTEIN; NATRIURETIC PEPTIDE;
D O I
10.1155/2020/2018035
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The use of a large number of cardiovascular biomarkers, meant to complement the use of the electrocardiogram, echocardiography cardiac imaging, and clinical symptom assessment, has become a routine in clinical diagnosis, differential diagnosis, risk stratification, and prognosis and guides the management of patients with suspected cardiovascular diseases. There is a broad consensus that cardiac troponin and natriuretic peptides are the preferred biomarkers in clinical practice for the diagnosis of the acute coronary syndrome and heart failure, respectively, while the roles and possible clinical applications of several other potential biomarkers are still under study. This review mainly focuses on the recent studies of the roles and clinical applications of troponin and natriuretic peptides, which seem to be the best-validated markers in distinguishing and predicting the future cardiac events of patients with suspected cardiovascular diseases. Additionally, the review briefly discusses some of the large number of potential markers that may play a more prominent role in the future.
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页数:14
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