Ocular manifestations of Weill-Marchesani syndrome. A review of ten cases

Weill-Marchesani syndrome is an uncommon congenital disease inherited on an autosomal recessive basis. Brachymorphic dwarfism is extremely suggestive. The severity of the condition is due to its ocular manifestations, which include a small spherical lens, dislocation of the lens, and glaucoma. Ten cases including four from the same family are reviewed. Dysmorphism and glaucoma were consistent features. Surgery was performed in most cases. An evaluation of medium-and long-term outcomes showed that the prognosis is guarded in the absence of early surgical treatment.