New Advances in Cervical Cancer: From Bench to Bedside

被引:53
|
作者
D'Oria, Ottavia [1 ]
Corrado, Giacomo [2 ]
Lagana, Antonio Simone [3 ]
Chiantera, Vito [3 ]
Vizza, Enrico [4 ]
Giannini, Andrea [1 ]
机构
[1] Sapienza Univ, PhD Course Translat Med & Oncol, Dept Med & Surg Sci & Translat Med, I-00185 Rome, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Salute Donna Bambino & Sanita Pu, I-00168 Rome, Italy
[3] Univ Palermo, Unit Gynecol Oncol, ARNAS Civ Di Cristina Benfratelli, Dept Hlth Promot Mother & Child Care Internal Med, I-90127 Palermo, Italy
[4] IRCSS Regina Elena Natl Canc Inst, Gynecol Oncol Unit, Dept Expt Clin Oncol, I-00144 Rome, Italy
关键词
cervical cancer; cancer therapy; gynecological cancer surgery; targeted therapy; SURGERY;
D O I
10.3390/ijerph19127094
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advantages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering oncological patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.
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页数:5
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