Rifampicin as treatment for pruritus in malignant cholestasis

被引:16
|
作者
Price, TJ [1 ]
Patterson, WK [1 ]
Olver, IN [1 ]
机构
[1] Royal Adelaide Hosp, Ctr Canc, Adelaide, SA 5000, Australia
关键词
rifampicin; pruritus; cholestasis; malignancy;
D O I
10.1007/s005200050210
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The efficacy and safety of using rifampicin to treat the pruritus associated with malignant cholestasis was evaluated. The outcomes of eight patients who received 150 mg rifampicin twice daily were reviewed. All responded, with six having complete resolution of the itch. Two patients were able to discontinue rifampicin following resolution of their cholestatic jaundice by surgery and chemotherapy respectively. No side effects were reported. Rifampicin is a safe effective treatment for the pruritus associated with cholestasis secondary to cancer.
引用
收藏
页码:533 / 535
页数:3
相关论文
共 50 条
  • [1] Rifampicin as treatment for pruritus in malignant cholestasis
    T. J. Price
    W. K. Patterson
    I. N. Olver
    [J]. Supportive Care in Cancer, 1998, 6 : 533 - 535
  • [2] EFFECT OF RIFAMPICIN IN THE TREATMENT OF PRURITUS IN HEPATIC CHOLESTASIS
    GREGORIO, GV
    BALL, CS
    MOWAT, AP
    MIELIVERGANI, G
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 1993, 69 (01) : 141 - 143
  • [3] Rifampicin as treatment for pruritus in malignant cholestasis: an example of an improper indication for anti-infective drugs
    Castagnola, E
    Viscoli, C
    [J]. SUPPORTIVE CARE IN CANCER, 1999, 7 (03) : 160 - 160
  • [4] Treatment of the pruritus of cholestasis
    Bergasa N.V.
    [J]. Current Treatment Options in Gastroenterology, 2004, 7 (6) : 501 - 508
  • [5] Rifampicin and treatment of cholestatic pruritus
    Hofmann, AF
    [J]. GUT, 2002, 51 (05) : 756 - 757
  • [6] Update on the Treatment of the Pruritus of Cholestasis
    Bergasa, Nora V.
    [J]. CLINICS IN LIVER DISEASE, 2008, 12 (01) : 219 - +
  • [7] The pruritus of cholestasis: treatment options
    Bergasa, NV
    [J]. GASTROENTEROLOGY YESTERDAY - TODAY - TOMORROW: A REVIEW AND PREVIEW, 2005, 144 : 203 - 209
  • [8] Refractory pruritus from malignant cholestasis: management
    Fernando, G. V. M. C.
    Preston, Nancy
    [J]. BMJ SUPPORTIVE & PALLIATIVE CARE, 2023, 13 (E1) : E78 - E80
  • [9] Pathogenesis and Treatment of Pruritus in Cholestasis
    Andreas E. Kremer
    Ulrich Beuers
    Ronald P. J. Oude-Elferink
    Thomas Pusl
    [J]. Drugs, 2008, 68 : 2163 - 2182
  • [10] Pathogenesis and Treatment of Pruritus in Cholestasis
    Kremer, Andreas E.
    Beuers, Ulrich
    Oude-Elferink, Ronald P. J.
    Pusl, Thomas
    [J]. DRUGS, 2008, 68 (15) : 2163 - 2182