Viral therapy for glioblastoma

被引：29
|
作者：
Chiocca, EA [1 ]
Aghi, M [1 ]
Fulci, G [1 ]
机构：
[1] Massachusetts Gen Hosp E, Mol Neurooncol Lab, Neurosurg Serv, Charlestown, MA 02129 USA
来源：
CANCER JOURNAL | 2003年 / 9卷 / 03期
关键词：
D O I：
10.1097/00130404-200305000-00005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Malignant gliomas remain amongst the most difficult cancer to treat. Viral-based gene therapies have been employed for the last decade in preclinical and clinical modes as a novel treatment modality. In this review, such therapies are summarized. The overwhelming majority of clinical studies point one to conclude that methodologies that will increase tumor infection/transduction will lead to enhanced therapeutic results.
引用
收藏
页码：167 / 179
页数：13
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