Identification of pituitary-specific transcription factor-1 (PIT-1) and leptin gene (LEP) polymorphism of Holstein cattle reared in Turkey

被引：0

作者：

Bayram, Davut ^{[1
]}

Arslan, Korhan ^{[2
]}

Akyuz, Bilal ^{[2
]}

Iscan, Kaan Muhsin ^{[1
]}

机构：

[1] 1Erciyes Univ, Dept Anim Breeding & Husbandary, Fac Vet Med, Kayseri, Turkey

[2] 1Erciyes Univ, Dept Genet, Kayseri, Turkey

来源：

ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI | 2017年 / 64卷 / 04期

关键词：

Holstein; leptin; pit-I; polymorphism; RFLP; MILK-PRODUCTION TRAITS; GROWTH-HORMONE GENE; DAIRY-COWS; PERFORMANCE TRAITS; BEEF-CATTLE; PCR-RFLP; ASSOCIATION; REPRODUCTION; BULLS; YIELD;

D O I：

10.1501/Vetfak_0000002818

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Purpose of this study was to examine leptin (LEP) and pituitary-specific transcription factor-1 (Pit-I) gene polymorphisms in Holstein cattle (n= 352) in Turkey. In order to determine the Pit-I-HinfI and LEP-Sau3AI polymorphisms, polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) were performed. A 600 bp length fragment of Pit-I and a 422 bp length fragment of LEP were amplified. In this study, two types of alleles, A and B, for both of the Pit-I and LEP genes were observed. The highest frequencies of the alleles were estimated, and were the B allele (0.68) for the Pit-I gene and the A allele (0.87) for the LEP gene. According to the results of the chi-square test, a significant deviation from the Hardy-Weinberg equilibrium was determined for both of these genes in the investigated breed (in the same order; X-2: 40.75, p<0.001and X-2: 8.4, p< 0.01).

引用

页码：337 / 343

页数：7

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