CYP2E1 overexpression sensitizes hepatocytes to JNK-dependent death from 4-hydroxynonenal

被引：0
|
作者：
Singh, R
Wang, YJ
Schattenberg, JM
Rigoli, RM
Czaja, MJ
机构：
[1] Albert Einstein Coll Med, Bronx, NY 10467 USA
[2] Med Klin & Poliklin 1, Mainz, Germany
来源：
HEPATOLOGY | 2005年 / 42卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：632A / 632A
页数：1
相关论文
共 50 条
  • [1] Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation
    Singh, Rajat
    Wang, Yongjun
    Schattenberg, Joern M.
    Xiang, Youqing
    Czaja, Mark J.
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2009, 297 (05): : G907 - G917
  • [2] The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
    Bardag-Gorce, F
    Li, J
    French, BA
    French, SW
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2005, 78 (02) : 109 - 115
  • [3] CYP2E1 expression sensitizes hepatocytes to death from polyunsaturated fatty acids through ERK signaling
    Schattenberg, JM
    Wang, YJ
    Rigoli, RM
    Czaja, MJ
    GASTROENTEROLOGY, 2003, 124 (04) : A706 - A707
  • [4] The effect of ethanol-induced CYP2E1 lipid peroxidation by-product 4-hydroxynonenal on the 26S proteasome
    Bardag-Gorce, F
    Li, J
    French, BA
    French, SW
    FASEB JOURNAL, 2003, 17 (04): : A325 - A325
  • [5] Increased cytochrome p450 2E1 (CYP2E1) expression sensitizes hepatocytes to TNF-A-induced cell death.
    Liu, HL
    Rubashevsky, E
    Jones, BE
    Czaja, MJ
    HEPATOLOGY, 2000, 32 (04) : 304A - 304A
  • [6] Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
    Bai, JX
    Cederbaum, AI
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (08) : 5128 - 5136
  • [7] Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
    Abdelmegeed, MA
    Carruthers, NJ
    Woodcroft, KJ
    Kim, SK
    Novak, RF
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 315 (01): : 203 - 213
  • [8] MECHANISM OF OXIDATION BY MITOCHONDRIAL CYP2E1 DIFFERS FROM MICROSOMAL CYP2E1
    Hartman, Jessica H.
    Martin, H. Cass
    Miller, Grover P.
    DRUG METABOLISM REVIEWS, 2015, 47 : 71 - 71
  • [9] Human CYP2E1 dependent formation of glycidamide from acrylamide
    Czech, E.
    Bernauer, U.
    Palavinskas, R.
    Klaffke, H. S.
    Gunderi-Reimy, U.
    Appel, K. E.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2007, 375 : 73 - 73
  • [10] CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
    Schattenberg, JM
    Wang, YJ
    Rigoli, RM
    Koop, DR
    Czaja, MJ
    HEPATOLOGY, 2004, 39 (02) : 444 - 455
12345